Natural Products Laboratory, Institute of Biology, Leiden University

Enter the name for this tabbed section: Metabolomics
In the past years several genomes have been completely sequenced and the genomes of more organisms are being sequenced. The number of fully sequenced organisms will grow exponentially. This will open novel possibilities of studying the functions of the genes in these organisms. Functional genomics requires a thorough definition of the phenotype, to be able to determine what changes result from up- or down-regulation of genes. A phenotype can be defined by morphological characteristics, by physiological measurements, as well as by biochemical (transcriptomics or proteomics) and chemical (metabolomics) analysis. In recent years more and more attention is being paid to the chemical characterization of the phenotype. Chemical characterization can be done on the level of macromolecules (e.g. proteomics and characterization of polysaccharides and lignins) or low molecular weight compounds (the metabolome). The metabolome consists of two types of compounds, the primary metabolites and the secondary metabolites. The primary metabolites are compounds involved in the basic functions of the living cell, such as respiration and biosynthesis of the amino acids and other compounds needed for a living cell. … Read more
Enter the name for this tabbed section: NADES
Most of metabolites of organisms are not soluble in water… Read more
Enter the name for this tabbed section: Chemical Ecology
Plants develops own defense mechanisms… Read more
Enter the name for this tabbed section: Biopesticide
In these days most of agricultural products are cultivated in large scale… Read more
Enter the name for this tabbed section: Microbial Metabolomics
Microorganisms are still attractive resource of medicine, particularly… Read more
Enter the name for this tabbed section: Plant Biotechnology
Plant produce huge number of secondary metabolites but the production yields are quite low… Read more
Enter the name for this tabbed section: Biosynthesis
Plants produce a wide range of metabolites using very sophisticated mechanisms… Read more
Enter the name for this tabbed section: Marine Metabolomics
Comparing with terrestrial plants marine organisms are not yet studied but the potential… Read more

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Metabolomics
NADES
Chemical Ecology
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Microbial Metabolomics
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Natural Products Laboratory
Institute of Biology
Leiden University
Sylviusweg 72
2333 BE Leiden
The Netherlands

Tel) +31 (0)71 527 4510
Fax) +31 (0)71 527 4511
E-mail) NPLadministrator@leidennpl.org